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Abdominal pain in pregnancy

Obstetrics

OB triage or the emergency department, any gestation

The first question

What gestation, and is the pain obstetric or not?

Two patients: the gestational age and the maternal stability first, then the fetal status.

  1. 01

    Gestational age

    Under 20 weeks: ectopic and miscarriage lead. Over 20: labour, abruption, preeclampsia, and the surgical causes that do not stop for pregnancy.

  2. 02

    Maternal stability and fetal status

    Vital signs, then the fetal heart rate and monitoring after viability.

  3. 03

    Obstetric or not

    Contractions, bleeding, fluid, hypertension say obstetric. Migration, anorexia, urinary symptoms and biliary pain say otherwise.

  4. 04

    Investigate without delay

    Ultrasound first; CT or MRI when the answer matters, because a missed appendicitis harms both patients more than the radiation.

Where it is

Each opens the structure on the 3D pelvis.

History that discriminates

  • Site, onset, character, radiation, relation to contractions
  • Bleeding, fluid, fetal movements
  • Headache, visual symptoms, epigastric pain (preeclampsia)
  • Urinary, bowel, biliary symptoms
  • Prior surgery, fibroids, ovarian cysts
  • Trauma

Examination that discriminates

  • Vital signs, temperature
  • Uterine tone and tenderness, contractions, fundal height
  • Site of maximal tenderness (the appendix migrates upward with the uterus), peritonism, Murphy's sign, renal angle
  • Fetal heart rate; monitoring after viability
  • Speculum and cervical assessment when labour or rupture is possible and praevia excluded

Investigations

  • Urinalysis and culture
  • CBC (leucocytosis is physiological), liver enzymes, lipase, urate, creatinine
  • Ultrasound: pregnancy, adnexa, appendix, kidneys, gallbladder
  • MRI without gadolinium for appendicitis when ultrasound is inconclusive
  • Fetal monitoring

The differential

DiagnosisFavoursAgainstUrgency
Labour (term or preterm)Regular painful contractions with cervical changeConstant pain without contractionsurgent
AbruptionConstant pain, hard tender uterus, bleeding, hypertensionSoft uterus, normal tracingemergent
Preeclampsia with HELLPEpigastric or right upper quadrant pain with hypertension, headache, abnormal liver enzymes and plateletsNormal blood pressure and bloodsemergent
AppendicitisMigration, anorexia, tenderness displaced upward, feverPain tied to contractionsemergent
PyelonephritisFever, flank pain, pyuria, rigorsNormal urineurgent
Ovarian torsion or cyst accidentSudden unilateral pain with vomiting, a known cyst, first or early second trimesterCentral painemergent
Degenerating fibroidKnown fibroid, localised tenderness over itNo fibroidroutine
Biliary colic or cholecystitisRight upper quadrant pain after meals, Murphy's sign, gallstones on scanNormal gallbladderurgent
Round ligament painSharp, brief, one-sided, with movement, second trimester, everything else normalConstant pain, any red flagroutine

Pitfalls this pathway refuses

  • Attributing pain to the pregnancy before excluding the causes that kill (appendicitis, abruption, HELLP)
  • Withholding imaging out of fear of radiation
  • Interpreting a white count of 14 as infection

Frameworks

  • Cunningham et al.: Williams Obstetrics, 26th edition (maternal physiology, labour mechanics, placental anatomy) (2022).
  • SOGC: Guideline 426: Hypertensive disorders of pregnancy, diagnosis, prediction, prevention and management (2022). Definitions and severity language follow the SOGC guideline; where ACOG terminology (preeclampsia with severe features) differs, the module names both.